Molecular parasitology goes cellular

Nanocavities: Optomechanics goes molecular.

Surface-enhanced Raman spectroscopy (SERS) is a technique capable of detecting and chemically identifying single molecules in the vicinity of nanostructured metal surfaces. In a typical Raman process, a photon is inelastically scattered from a molecule, exchanging energy with its vibrations and carrying away its molecular fingerprint encoded in the loss or gain of energy. In SERS, this signal i...

Molecular parasitology in the 21st century.

Protist parasites cause important human and animal diseases, and because of their early divergence from other eukaryotes they possess structural and biochemical characteristics not found in other cells. The completion of the genome projects of most human protist parasites and the development of novel molecular tools for their study guarantee a rapid progress in understanding how they invade, mo...

Chemical biology: Chromatin chemistry goes cellular.

Parasitology

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Molecular & Biochemical Parasitology New insights into parasite rhomboid proteases

The rhomboid-like proteins constitute a large family of intramembrane serine proteases that are present in all branches of life. First studied in Drosophila, these enzymes catalyse the release of the active forms of proteins from the membrane and hence trigger signalling events. In protozoan parasites, a limited number of rhomboid-like proteases have been investigated and some of them are assoc...